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John Vaccaro (johniac)<p>SciTech Chronicles.. . . . .May 13th, 2025</p><p><a href="https://bit.ly/stc051325" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">bit.ly/stc051325</span><span class="invisible"></span></a></p><p><a href="https://mastodon.social/tags/AEM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AEM</span></a> <a href="https://mastodon.social/tags/PEM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PEM</span></a> <a href="https://mastodon.social/tags/Alkaline" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Alkaline</span></a> <a href="https://mastodon.social/tags/nickel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>nickel</span></a> <a href="https://mastodon.social/tags/pozzolana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pozzolana</span></a> #"lime clasts" <a href="https://mastodon.social/tags/quicklime" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>quicklime</span></a> #"hot mixing" <a href="https://mastodon.social/tags/wastewater" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>wastewater</span></a> #"genetic material" <a href="https://mastodon.social/tags/sequencing" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>sequencing</span></a> <a href="https://mastodon.social/tags/PCR" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PCR</span></a> <a href="https://mastodon.social/tags/genomes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>genomes</span></a> <a href="https://mastodon.social/tags/CCR5" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CCR5</span></a> #"1000 Genomes Project" <a href="https://mastodon.social/tags/chemokines" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>chemokines</span></a> <a href="https://mastodon.social/tags/industrial" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>industrial</span></a> <a href="https://mastodon.social/tags/enol" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>enol</span></a> <a href="https://mastodon.social/tags/light" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>light</span></a>-powered <a href="https://mastodon.social/tags/separation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>separation</span></a></p>
-0--1-<p><span class="h-card" translate="no"><a href="https://genomic.social/@dnavinci" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>dnavinci</span></a></span> My career was with pharma, pbm and biotech on the business/operations side. I've <a href="https://mastodon.social/tags/conSLUTed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>conSLUTed</span></a> for most. Just <a href="https://mastodon.social/tags/MUTYH" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MUTYH</span></a> and <a href="https://mastodon.social/tags/CCR5" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CCR5</span></a>-Δ32. The irony is I'm gay and taught in Africa during the <a href="https://mastodon.social/tags/AIDSHIV" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AIDSHIV</span></a> epidemic but didn't know I was immune--and I didn't fuck around--but was scared to death of HIV and didn't have to be. It's like that old <a href="https://mastodon.social/tags/AlanisMorrisette" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AlanisMorrisette</span></a> song <a href="https://mastodon.social/tags/IsntItIronic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>IsntItIronic</span></a>: <a href="https://youtu.be/Jne9t8sHpUc?feature=shared" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">youtu.be/Jne9t8sHpUc?feature=s</span><span class="invisible">hared</span></a></p>
Norobiik @Norobiik@noc.social<p>Edmonds, of Desert Hot Springs, <a href="https://noc.social/tags/California" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>California</span></a>, underwent a treatment in which he received <a href="https://noc.social/tags/StemCells" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>StemCells</span></a> with a rare <a href="https://noc.social/tags/GeneticMutation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>GeneticMutation</span></a> that makes people who have it resistant to acquiring <a href="https://noc.social/tags/HIV" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>HIV</span></a>. The <a href="https://noc.social/tags/StemCell" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>StemCell</span></a> transplant came from a donor with the rare homozygous <a href="https://noc.social/tags/CCR5" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CCR5</span></a> delta mutation.</p><p>Man in <a href="https://noc.social/tags/remission" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>remission</span></a> from blood cancer and HIV after remarkable treatment | <a href="https://noc.social/tags/Leukemia" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Leukemia</span></a><br><a href="https://www.theguardian.com/us-news/2024/feb/28/blood-cancer-hiv-treatment" rel="nofollow noopener" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">theguardian.com/us-news/2024/f</span><span class="invisible">eb/28/blood-cancer-hiv-treatment</span></a></p>
joe•iuculano :mastodon:<p>A man known as the “ <a href="https://masto.ai/tags/GenevaPatient" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>GenevaPatient</span></a> ” has become the latest person in the world to be cured of <a href="https://masto.ai/tags/HIV" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>HIV</span></a> after a <a href="https://masto.ai/tags/StemCellTransplant" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>StemCellTransplant</span></a> for <a href="https://masto.ai/tags/Cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer</span></a> treatment.<br>While there have been five other known cases of people who have been cured of HIV - meaning they have been declared in long-term remission - his case is so far unique. He’s the only one who received <a href="https://masto.ai/tags/StemCells" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>StemCells</span></a> from a donor who does not have a rare gene mutation - <a href="https://masto.ai/tags/CCR5" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CCR5</span></a> - that blocks HIV from entering cells.</p><p><a href="https://masto.ai/tags/Cure" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cure</span></a> <a href="https://masto.ai/tags/AIDS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AIDS</span></a></p><p><a href="https://www.euronews.com/next/2023/07/20/geneva-patient-becomes-first-to-be-cured-of-hiv-after-normal-stem-cell-transplant" rel="nofollow noopener" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">euronews.com/next/2023/07/20/g</span><span class="invisible">eneva-patient-becomes-first-to-be-cured-of-hiv-after-normal-stem-cell-transplant</span></a></p>
halama_immuno<p><a href="https://mstdn.science/tags/macrophages" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>macrophages</span></a> can be selectively modulated through <a href="https://mstdn.science/tags/cytokines" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cytokines</span></a> : <a href="https://mstdn.science/tags/CCR5" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CCR5</span></a> and CCR1 mediates re-polarization. <a href="https://mstdn.science/tags/innateimmunity" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>innateimmunity</span></a> in Action for <a href="https://mstdn.science/tags/Immunotherapy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Immunotherapy</span></a> in <a href="https://mstdn.science/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancer</span></a><br><a href="https://jitc.bmj.com/content/10/1/e003131" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jitc.bmj.com/content/10/1/e003</span><span class="invisible">131</span></a></p>
Joseph P.<p>98% of the CD3+ <span class="h-card"><a href="https://a.gup.pe/u/lymphocyte" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>lymphocyte</span></a></span> s in the resection specimens were positive for PD-1, which is a molecule that helps to regulate the activity of the immune system.</p><p><a href="https://mstdn.science/tags/CCL5" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CCL5</span></a> is a protein produced by T cells, which are a type of white blood cell. <a href="https://mstdn.science/tags/CCR5" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CCR5</span></a> is a receptor found on metastatic tumor cells, which are cancer cells that have spread from the primary <a href="https://mstdn.science/tags/tumor" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tumor</span></a> to other parts of the body.</p>