**Causal effects of physical activity and screen time on childhood intelligence via Mendelian randomization: The mediating role of intracranial volume**
“_Our two-sample MR analysis revealed a positive causal effect of moderate to vigorous physical activity (PA) on childhood IQ (β = 0.42, 95 % confidence interval (CI): [0.12, 0.72], p = 6.26 × 10−3), whereas leisure screen time (LST) exhibited a negative causal effect (β = −0.35, 95 % CI: [ −0.60, −0.10], p = 5.59 ×10−3). Reverse MR analysis found no evidence of causations._”
Feng, J., Wan, Y., & Zhang, L. (2025). Causal effects of physical activity and screen time on childhood intelligence via Mendelian randomization: The mediating role of intracranial volume. Developmental Cognitive Neuroscience, 74, 101586. https://doi.org/10.1016/j.dcn.2025.101586.
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