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Arjan Boltjes<p>... specific functional expression programs correlated with fluctuations in various <a href="https://mastodon.social/tags/Tcell" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Tcell</span></a> subsets, which may be associated with <a href="https://mastodon.social/tags/AML" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AML</span></a> progression and relapse. Furthermore, our analysis of cellular communication networks led to the identification of <a href="https://mastodon.social/tags/VISTA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>VISTA</span></a>, <a href="https://mastodon.social/tags/CD244" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CD244</span></a>, and <a href="https://mastodon.social/tags/TIM3" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>TIM3</span></a> as potential <a href="https://mastodon.social/tags/immunotherapeutic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>immunotherapeutic</span></a> targets in pediatric AML."</p><p><a href="https://pubmed.ncbi.nlm.nih.gov/38844062/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/388440</span><span class="invisible">62/</span></a></p><p>Nice work by Yuan et al., using <a href="https://mastodon.social/tags/scRNAseq" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>scRNAseq</span></a> and <a href="https://mastodon.social/tags/scTCRseq" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>scTCRseq</span></a>. No huge discoveries, but of interest nonetheless.</p><p><a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a> <a href="https://mastodon.social/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancer</span></a> <a href="https://mastodon.social/tags/immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>immunology</span></a></p>
DiverseTCR<p>It's almost become <a href="https://mstdn.social/tags/fancy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>fancy</span></a> to do <a href="https://mstdn.social/tags/scTCRseq" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>scTCRseq</span></a> and make conclusions on <a href="https://mstdn.social/tags/specificity" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>specificity</span></a> ...we are no where close to it...read this carefully. <a href="https://mstdn.social/tags/Amazing" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Amazing</span></a> <a href="https://mstdn.social/tags/TCRs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>TCRs</span></a> <a href="https://www.nature.com/articles/s41577-023-00835-3" rel="nofollow noopener" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41577-023</span><span class="invisible">-00835-3</span></a></p>